Thursday, March 21, 2013

Agmatine Sulfate


Agmatine Sulfate
CAS No.: 2482-00-0
Synonyms:(4-Aminobutyl)guanidinium sulphate; 1-Amino-4-guanidinobutane sulfate salt; 4-Guanidinobutylamine sulfate salt; N-(4-Aminobutyl)guanidine sulfate salt
MF: C5H14N4.H2SO4
EINECS No.: 219-617-3
What is Agmatine sulfate?
From Wikipedia, Agmatine is naturally produced in the body from the action of a particular enzyme which transforms L-Arginine to Agmatine. Supplementing with agmatine sulfate does many of the same things that arginine should do, but it seems to be much more effective. Agmatine sulfate has many benefits to the bodybuilder or athlete. The benefits of agmatine sulfate include enhanced muscle pumps, better nutrient partitioning (more calories are shuttled towards muscle tissue and less are stored as fat), and increased production of luteinizing hormone and growth hormone. Agmatine is the new and more effective supplement to increase Nitric Oxide Production. Directly supplementing with Agmatine Sulfate has proven to be much more effective in nutrient transport, partitioning, and enhancing bloodflow than taking Arginine.  Besides the incredible advantages that Agmatine gives you for athletics and performance, supplementing with Agmatine Sulfate has been proven to help with pain prevention and even enhance brain cognition with zero side effects. 

1.       Enhance Muscle pumps.
Agmatine sulfate appears to boost muscle pumps in a couple different ways. First, agmatine sulfate may improve nutrient partitioning, leading to more muscle glycogen (carbohydrates stored in muscle tissue) stored and consequently more water retained in the muscle. This can lead to a full look to the muscle and increase muscle pumps. Agmatine has been used for awhile now in the bodybuilding community as a supplement to help in the quest for increased muscle mass. As a potential strong neurotransmitter, it can improve the mind-muscle connection to improve the contractive efforts of our muscles. Stronger, more directed contractions can help promote improved effectiveness of exercises.

2.       Increase nitric oxide production
The nutrient partitioning effects of agmatine may be due to its possible ability to increase the insulin response to carbohydrates, and it may also have something to do with the increased blood flow to the muscle experienced with increased nitric oxide production.
3.       Increase LH and GH level.
Agmatine sulfate may play a role in the hypothalamic control of luteinizing hormone and growth hormone release, leading to increased levels of these hormones. Luteinizing hormone stimulates male Leydig cells to produce testosterone.
4.       Reduce pain. 
In addition, the pain reducing effects of Agmatine can not only be helpful in chronic pain conditions limiting exercise, but may also improve the endurance capacity as pain can often be a limiting factor to performance. Agmatine’s possible ability to regulate insulin production and increase the uptake of glucose may offer benefits for glycogen storage as well as a downgrade in the amount of glucose being transformed into fat.

As a result of these effects, supplementation with agmatine sulfate may improve athletic performance, increase muscle size, fullness, and vascularity, and may also increase fat loss. It may also have a couple of additional benefits like protection against free radical damage and an antidepressant effect. Arginine worked, but agmatine sulfate appears to be an even better option in terms of physique development and performance.

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