Plant extract Beta-Ecdysterone 98%HPLC

Plant extract Beta-Ecdysterone 98%HPLC/ Cyanotis Arachnoidea Root Extract

Botanical source: Cyanotis Arachnoidea Extract

CAS: 5289-74-7

Appearance: Light Yellow fine powder / White Crystalline Powder

Part used:root

Synonyms: β-Ecdysone, Cyanotis Extract, Cyanotis Arachnoidea Extract,  ecdysterone, 20-Hydroxyecdysone,  isoinokosterone,

Beta Ecdysterone 95% Cyanotis Extract

What is Beta-Ecdysterone?

Beta ecdysterone , according to wikipedia, also known as ecdisten, ecdysone, isoinokosterone and 20-hydroxyecdysone,  is what is known as a "plant sterol" : a compound found in plants that is structurally similar to anabolic human steroids such as testosterone.  However, beta ecdysterone is a plant sterol; NOT a steroid.

It was first discovered in insects and it was found that they depended upon it for survival. Speculation then arose as to whether the presence of beta ecdysterone in insects played a role in their remarkable body size to strength ratio.

Scientists discovered that ecdysterone could be found occurring naturally in certain herbs (rhaponticum/leuzeae and cyanotis vaga) and eventually developed methods to create high potency extractions.

How does Beta-Ecdysterone work?

Beta Ecdysterone stimulates protein metabolism. Higher levels of protein metabolism will lead to a positive nitrogen balance in your body. Like an air balloon expanding, your muscles will grow. The balloon will not expand without air the same as your muscles won’t grow without protein synthesis. Beta Ecdysterone dramatically increases the synthesis, leaning to significant muscle gain and straight increase.

Benefits of Beta Ecdysterone extract supplement

Beta-ecdysterone also often marketed as a natural alternative to steroids with claims that it's a powerful growth promoter with no negative hormonal consequences. Beta-ecdysterone is used widely by body builders with hopes to build muscle or lean body tissues. The key benefits of Beta-ecdysterone are summarized as below:

1. build lean body mass

 Beta-ecdysterone promotes protein synthesis, which enhances lean body mass when accompanied by resistance training, but the evidence is lacking and inconsistent. Its purpose is to stimulate cellular and muscle recovery so if this actually is true, combining this supplement with high biological value proteins, like animal protein—milk, chicken, eggs, fish—will improve results.

2. Help fat burning

Beta-ecdysterone works by blocking alpha adrenoreceptors. There are a number of feedback mechanisms that prevent the release of norepinephrine (NE), one of the body's primary lipolytic hormones. When NE is released, such as in periods of stress or after taking a sympathomimetic (such as ephedrine), it stimulates both the alpha and beta adrenoreceptors. Stimulation of the beta adrenoreceptors causes the breakdown of fat while stimulating the alpha adrenoreceptors has the opposite effect, preventing the release of NE and lipolysis. Beta-ecdysterone prevents this negative feedback mechanism, thus increasing NErelease and lipolysis.

3. help treat osteoporosis

 Chinese researchers found that beta-ecdysterone treatment alleviated osteoporosis symptoms in mice without any obvious side effects.  Experts concluded that beta-ecdysterone may be a promising candidate drug for the treatment of osteoporosis but more testing is necessary before it can be approved for human treatment.

4. help lower blood glucose levels

In a recent study beta-ecdysterone was found to help lower blood glucose levels—in patients in the normal to moderate blood glucose range—without altering insulin levels. Therefore, it could be of benefit in the treatment of type-II diabetes, and may aid weight loss.

Doasge of Beta-ecdysterone supplement

Studies have shown that supplementation with beta-ecdysterone is safe at dosages of 5 milligrams per kilogram of bodyweight. However, most nutritional companies use significantly lower dosages—about 50-90 mg total. And so many say that athletes would need a much larger dosage than what's included in most nutritional formulas in order to see and muscle growth-related benefits.

Stanford Ingredients Co., Ltd is a professional manufacturer and supplier of Sulbutiamine for the industry of bodybuilding,  dietary supplements, and sports nutriton ingredients. We guarantee you the best raw materials via breaktrough technology and customer service.

Vinpocetine99%- Neuronal Antioxidant as Cognitive ingredient supplement

Vinpocetine99%- Neuronal Antioxidant as Cognitive ingredient supplement

chemical name: ethyl apovincaminate

botanical source: periwinkle plant

Synonyms: Vincamine, Vinca Minor, Periwinkle Extract, Cavinton

CAS No. :42971-09-5

Molecular Formula: C22H26N2O2

Molecular Weight: 350.45

assay:99%min

Appearance: white powder

packing:25kg/drum

What is vinpocetine?

Vinpocetine is an extract from the seeds of the periwinkle plant (Vinca minor), a common, vinelike evergreen ground cover. Vinpocetine is a derivative of the alkaloid vincamine. Like vincamine, it is found in small amounts in the seeds of periwinkle as well as other plants, such as voaconga andCrioceras longiflorus. Throughout the world, vincamine has been used to treat senile dementia with significant success. Studies have found vinpocetine to demonstrate many of the same functions as those of vincamine, but without the side effects.

There are actually over 50 alkaloids presents in the Vinca Minor, of which vinpocetine is thought to be the superior and most researched compound, due to low its low toxicity and reported benefits. Additionally, it is reported to be better than vincamine at improving memory and circulation in the brain.

How does vinpocetine work?

Numerous scientific studies have shown vinpocetine to be of benefit for the prevention and improvement of many different kinds of ailments. It enhances cognitive functions, including those involving long- and short-term memory, and it has also been shown to be valuable in protecting heart, visual, and hearing functions, among other benefits.

In broadest terms, vinpocetine is a powerful memory enhancer. It achieves this principally by facilitating cerebral metabolism and improving blood flow in the brain. It works by causing mild dilation of blood vessels, thereby allowing for increased cerebral blood flow, which results in increased oxygenation and glucose utilization.

This makes vinpocetine an ideal candidate not only for the improvement and prevention of certain disease processes in need of increased blood flow and oxygenation, but also for athletes who want to enhance their performance by increasing brain oxygenation, such as skiers, mountain climbers, and high-altitude hikers.

Benefits of taking vinpocetine supplement

1.Improves Memory

The main purpose of vinpocetine is to enhance memory and cognition. It also improves awareness and alertness. People who suffer short as well as long-term memory loss can benefit from vinpocetine. What does vinpocetine exactly do to overcome memory loss? Well, it increases dilation of blood vessels, promotes blood circulation in the brain, and improves oxygen usage.

2. Treats Hair loss

Since vinpocetine is a natural cerebral vasodilator, it can be highly effective for treating hair loss. If you are experiencing hair loss since a very long time, you should begin using vinpocetine. It can offer better protection to your hair without any side-effects unlike other chemical treatments.

3. Improves Cognition

Again, as vinpocetine is excellent in blood circulation in the brain, it makes a great contribution in improving the cognitive function, especially for people in advanced age groups. It enhances neuronal plasticity which has been reported to be a spatial memory booster in animal models while improving cognitive performance in human beings.

Dosage of Vinpocetine

Although vinpocetine is the best medicine for boosting memory and concentration, it should always be consumed after doctor's consultation and in correct dosage. It is recommended to consume vinpocetine more than once daily however, some people may be sensitive to such a dose. it is better to consume a 5mg vinpocetine for the first time and look for any allergic reactions by your body or other negative responses. By doing this you can prevent possible side-effects of vinpocetine. Then you can move on to 10 mg dosage once you are familiar with 5mg dosage.

Stanford Ingredients Co., Ltd is a professional manufacturer and supplier of Vinpocetine for the industry of bodybuilding,  dietary supplements, and sports nutriton ingredients. We guarantee you the best raw materials via breaktrough technology and customer service.

bacopa monnieri extract 20% Bacopaside Chinese herbal nootropics

bacopa monnieri extract 20% Bacopaside Chinese herbal nootropics

Latin Name: Bacopa monnieri (L.) Wettst.

Synonyms: baocopa extract, Brahmi, Aindri, Lysimachia monnieri L. Cent., Graticola monnieri L., Herpestis monniera L. Kunth., Water hyssop, Thyme-leafed gratiola, Indian Pennywort

Specification: Bacopaside 20%~50% HPLC

Appearance: Yellow brown fine powder

CAS No.: 382146-66-9

What is bacopa monnieri extract?

Bacopa monnieri extract, according to Wikipedia, is an herb native to India that has a long history of use in the Ayurvedic system of medicine where it is known as Brahmi. Bacopa monnieri is one of the most important herbs in India and is used for a wide variety of ailments and as a general tonic and an anti-aging herb. In the west, Bacopa monnieri is gaining popularity due to recent studies that examine its effect on the brain, cancer and it ability to keep stress at bay. There are many other names for bacopa monnieri extract,such as  water hyssop, water purslane , Bacopa monnieri (L.) Wettst ,Brahmi, etc. Brahmi is also the name given to Centella asiatica, particularly in North India.

What are in the bacopa monnieri extract

From wikipedia, Bacopa monnieri has many chemical constituents It contains saponins, designated as bacopaside I, II, III, IV and V. Additional phytochemicals betulinic acid, wogonin and oroxindin have been isolated from the aerial parts. This herb also has the flavonoids luteolin and apigenin. Dammarane-type triterpenoid saponins classified as pseudojujubogenin and jujubogenin glycosides are reported as some of the active components in this plant. Bacoside A, the bioactive component of this Indian medicinal plant is a mixture of saponins with bacoside A3, bacopaside II, jujubogenin isomer of bacopasaponin C and bacopasaponin C as major constituents.

Benefits of taking Bacopa monnieri extract

Bacopa monnieri extract is considered to be a nerve and brain tonic in Ayurvedic and Chinese medicine and is used to treat epilepsy, sexual dysfunction and fertility problems. Bacopa monnieri may be helpful in treating memory problems and depression in the elderly. Some key benefits of bacopa are sumarrized as below:

1.Enhance memory.

 Bacopa monnieri extract has many Cognitive Functions known as a brain tonic because it can be used to improve learning problems, memory, and concentration.

2.Enhance mood and reduce anxiety

Bacopa monnieri supports the effects of certain neurotransmitters, including serotonin and acetylcholine, states the University of Michigan Health System. This effect on neurotransmitters is what enables Bacopa monnieri to support mood-related symptoms. According toDrug Digest, animal studies of Bacopa monnieri’s effectiveness in treating mood issues have produced positive results, finding that Bacopa monnieri was nearly as effective as common prescription anti-anxiety medications, but without the side effects.

3. Cancer Prevention and Treatment

 Bacopa has long been used in the treatment of cancer in Ayurvedic medicine.

SIDE EFFECTS OF BACOPA MONNIERI

Long term side effects and safety of bacopa monnieri extract are currently not fully known. As with most herbs, it's best to take breaks from use.

Dosage of Bacopa monnieri extract supplement

There is no specified dosage for Bacopa monnieri. Some companies suggest 100mg daily but some supplement brands suggest 2 tablets of 225mg twice daily.Therefore, There is no right dosage that applies to everyone, each person is unique. In general use the lowest dosage that works. The usual dosage is 100 mg to 300 mg of the extract once or twice daily. It appears that it works better when taken a few days in a row rather than just once.

Stanford Ingredients Co., Ltd is a professional manufacturer and supplier of Bacopa monnieri extract for the industry of bodybuilding,  dietary supplements, and sports nutriton ingredients. We guarantee you the best raw materials via breaktrough technology and customer service.

Noopept

Noopept 99%

CAS: 157115-85-0

Chemical name: N-(1-(Phenylacetyl)-L-prolyl)glycine ethyl ester

Synonyms: Ноопепт,Noopeptide,GVS-111, N-phenylacetyl-L-prolylglycine ethyl ester

Molecular Formula: C17H22N2O4

Molecular Weight: 318.37

Appearance:White or colourless crystalline powder

What is noopept?

Noopept is a nootropic compound that was first discovered in Russia. It has shown to be 1000 times more potent than Piracetam, the most popular of the racetam family. On a structural basis, Noopept is a dipeptide conjugate of Piracetam. According to Wikipedia, Noopept has many other names such as Ноопепт; GVS-111, N-phenylacetyl-L-prolylglycine ethyl ester. In research, Noopept has displayed significant neuroprotective properties. It has also been shown to enhance the activity of the immune system in both healthy and immune-compromised animals.

How does noopept work?

 Noopept works on the AMPA and NDMA rector sites and their pathways of function. It also has an affinity with the Acetylcholine system and the ACh receptor sites. Both of these factors contribute to Noopept’s array of nootropic benefits.

Like Aniracetam, Noopept seems to stimulate an anxiolytic response in animal and human models. This is not a guaranteed result and seems to vary widely between subjects. Like with Aniracetam, Noopept seems stimulate Dopamine receptor sites (D2 and D3) as well as the ACh nicotinic receptor sites. Noopept also seems to stimulate certain Serotonin receptors and this may also lead to mood boosting qualities.

Benefits of taking noopept supplement

Noopept is commonly prescribed as a general nootropic in many countries and a Cognitive Health Supplement ingreidnets uesd in sports nutrition. Its key benefits are summarized as below:

1.Improves Memory and Learning

Noopept’s most emphasized benefit is how it can enhance memory and improve the learning process. Noopept, like Piracetam, assists with memory formation, but with additional benefits not present in the latter, which are memory consolidation and memory retrieval. Noopept facilitates the proper management of all forms of stimuli as they are processed by the brain, which allows for better retrieval of memory. In other words, signals being processed by our senses are more streamlined as they are transported into our brains in the form of memory.

2.Boost Mood

It can reduced anxiety and depression Symptoms,thus improve mood.

3.Treatment of Alzheimer's disease

Studies show that Noopept has high neuroprotective properties. The stimulation of the neurons caused by the health supplement prevents oxidative damage and apoptosis in the human brain. Many patients dealing with cognitive impairment regularly can benefit from a regular dosage of Noopept to prevent further dissociative cognitive functions.

Dosages of noopept supplement

The recommended dose of this supplement is between 10-20 mg daily. This can be taken in divided doses throughout the day, as desired. It is recommended to start on the low side and adjust as needed. Since this is a powder, having a good milligram scale is essential.

Sulbutiamine- nootropic

Sulbutiamine

CAS No.: 3286-46-2

Synonyms: Arcalion, Enerion, Bisibuthiamine, Youvitan

Molecular Formula:C32H46N8O6S2

Molecular Weight: 702.89

What is Sulbutiamine?

Sulbutiamine, accordingto wikipedia, as a synthetic derivative of thiamine (vitamin B1), it is a lipophilic compound that crosses the blood–brain barrier more readily than thiamine and increases the levels of thiamine and thiamine phosphate esters in the brain.

Does Sulbutiamine work?

Sulbutiamine, similar to coffee, easily crosses a person's blood brain barrier. This enables these two drugs to contact your mind and produce an extremely apparent effect. Both of these supplements then impact quantities/effects of distinct neurotransmitters in your brain. Neurotransmitters are the brain's manner of interacting with itself. Theoretically, in the event that an individual had zero neurotransmitters, you would be wholly brain dead.

Caffeine minimizes the effects involving the neurotransmitter adenosine. Because adenosine helps bring about sleep and inhibits alertness, caffeine will give you a rush of energy. Nonetheless, it won't affect the numbers of adenosine, it merely keeps their effects in check. While the caffeine wears away, the adenosine begins to be effective yet again, and you will most certainly crash.

Sulbutiamine effects absolutely different neurotransmitters. It raises amounts of ACh, GABA, and Glutamate. GABA improves mood plus reduces stress and anxiety. Glutamate and ACh work together to improve a person's memory and decrease levels of fatigue.

Benefits of taking Sulbutiamine supplement:

Sulbutiamine is a nootropic designed to give you more energy, improve your mood, and boost your memory.  The detailed benefits are summarized as below:

1.boost more energy

Sulbutiamine’s nootropic properties boost both physical and mental levels in the body leaving you with a feeling of high energy. It is used primarily to treat a condition called asthenia and fatigue.

2.improve mood

Sulbutiamine is another great nootropic to help with mood. Some people have compared Sulbutiamine to MDMA’s anxiolytic and anti-depressant qualities without the amphetamine stimulation. This is a rather bold statement but is likely proof that this B1 Vitamin derived nootropic may have some great mood boosting qualities. Sulbutimaine defiantly works for some and has been prescribed in countries outside North America to help with depression.

Sulbutiamine’s effects on mood are likely related to effects it has on dopamine. This nootropic increases dopamine and dopamine (D1) receptor density in the prefrontal cortex. Dopamine transmission problems are often a cause of depression. This would explain Sulbutiamines’ effects on possible mood improvement. It was also seen in a study to reduce behavioural inhibitions which are commonly seen in peoples with shyness and depression.

3.boost memory

Also from wikipeidia reference citation, Several studies have shown that sulbutiamine improves memory through the potentiation of cholinergic, dopaminergic, and glutamatergic transmission. When sulbutiamine is administered to mice, they perform better on operant conditioning tests[14] and object recognition tests.[15] Sulbutiamine also reduces the amnesiac effects of dizocilpine and improves memory in schizophrenics.

4. Erectile dysfunction

According to one recent study, sulbutiamine is effective for the treatment of psychogenic erectile dysfunction.

Sulbutiamine Dosage

The recommended Sulbutiamine dosage is usually 600 mg per day, taken in three 200 mg doses, one in the morning and one in the afternoon and another in the evening. It is sold in tablet capsule and powder form, generally in doses 200 mg each.

3,3′-Diindolylmethane(DIM)

3,3′-Diindolylmethane

Molecular Formula: C17H14N2 
Molecular weight: 246.31 
CAS#: 1968-05-4 

Appearance: Off- white to white crystalline powder

Synonyms:DIM, Diindolylmethane, Diindolyl methane;Diindolymetano

What is 3,3′-Diindolylmethane?

3,3′-Diindolylmethane, from Wikipedia description, also commonly known as DIM, is a natural substance produced when the body breaks down indole-3-carbinol, a compound found in the following vegetables:broccoli, Brussel sprouts, cabbage, cauliflower, collard greens, kale, mustard greens, watercress,etc.

How Does 3,3′-Diindolylmethane Work?

3,3′-Diindolylmethane stimulates more efficient estrogen metabolism. Supplementing the diet with DIM and eating cruciferous vegetables increases the specific aerobic metabolism for estrogen, multiplying the chance for estrogen to be broken down into its beneficial, or "good" estrogen metabolites. These "good"estrogen metabolites are known as the 2-hydroxy estrogens. Many of the benefits that are attributed to estrogen, which include its ability to protect the heart and brain with its antioxidant activity, are now known to come from these "good" metabolites.

When 3,3′-Diindolylmethane(DIM) increases the "good" estrogen metabolites, there is a simultaneous reduction in the levels of undesirable or "bad" estrogen metabolites. These include the 16-hydroxy estrogens, which are not antioxidants and can actually cause cancer. Greater production of these "bad" estrogen metabolites is promoted by obesity and exposure to a number of manmade environmental chemicals. These "bad" estrogen metabolites are responsible for many of estrogen's undesirable actions in women and men, including further unwanted weight gain, breast cancer, and uterine cancer.

In addition, a slow metabolism of estrogen, which leaves too much unmetabolized active estrogen known as estradiol in the body, can be a problem for both women and men. Elevated estradiol causes moodiness and breast pain in women and loss of sex drive in men. By promoting a healthy estrogen metabolism, DIM adjusts the balance of estradiol to its "good" metabolites. This also can result in a more desirable action fro testosterone. Testosterone supports energy and mood and helps sustain interest in sex in both men and women. When supplemental DIM is taken along with a program of regular exercise, it can help estrogen and testosterone contribute to good physical conditioning.

Benefits of taking 3,3′-Diindolylmethane(DIM) supplement

1. Estrogen Metabolism

Taking Diindolylmethane supplements increases the efficiency of the metabolic processing of estrogen. This increase in efficiency has been linked to increased antioxidant protection of the heart and brain. This process is also responsible for other benefits, such as an increase in libido in men and women and a decrease in moodiness for women.

2. Hormonal Balance

Diindolylmethane also appears to promote a healthy balance of testosterone in the body. Testosterone supports energy, promotes a happy mood and helps to maintain a healthy sex drive. In addition, Zeligs states that DIM may have an anti-aging effect and may help encourage lean body mass. When combined with exercise, it can increase muscle mass. These benefits are speculative, however, and more research needs to be done to confirm the efficacy of these claims.

3. Anticancer Benefits

According to Memorial Sloan-Kettering Cancer Center, DIM has been found to help prevent and treat breast and prostate cancers. Studies done on animals also found DIM to prevent the replication and spreading of cancer cells. Exactly how DIM helps to prevent and treat cancer is unknown; however, DIM inhibits angiogenesis, which is the formation of new blood vessels. Tumors require the growth of new blood vessels to supply the nourishment that is necessary for tumors to thrive. By preventing the growth of new blood vessels, DIM may therefore help to abolish tumors. Unfortunately, only a few small studies have been done on DIM so far, and more research needs to be done to confirm the usefulness of DIM as an anticancer supplement.

N-Methyltyramine-fact burner,stimulant

N-Methyltyramine

CAS: 370-98-9

Synonyms:4-hydroxy-N-Methyltyramine;Methyl-4-tyramine;NMT; N-Methyl-4-hydroxyphenylethylamine;N-Methyl-Tyramine; 4-[2-(Methylamino)ethyl]phenol

Molecular formula: C9H13NO

Molecular weight: 151.21

What is N-Methyltyramine?

N-Methyltyramine, as described in Wikipedia,  is a natural phenethylamine alkaloid found in a variety of plants, such as in barley, Citrus aurantium, etc. N-Methyltyramine, shortened as NMT, has many other names, some popular name such as N-Methyl-Tyramine, 4-hydroxy-N-Methyltyramine and 4-[2-(Methylamino)ethyl]phenol hcl. Citrus aurantium, known as bitter orange, is the best natural source of N-Methyltyramine. In addition, Studies of Acacia species have shown the presence of significant levels of NMT in their leaves. N-Methyltyramine is converted to Synephrine by Dopamine β –hydroxylase since NMT and synephrine are the main ingredients found in citrus fruit.

How does N-Methyltyramine work?

N-Methyltyramine HCL has been shown to work primarily as an alpha2-adrenoceptor antagonist, which are the GOOD things that norepinephrine provides us with. It creates a situation with insulin that allows you to burn fat.

The NMT HCl salt boosted the production of norepinephrine (NE) by the heart by a bit over 35%, compared to control.That was over the course of 2 hours — perfect for your workout and a bit of a rush afterward so you can get back to work or whatever you were doing.

Benefits of taking N-Methyltyramine

N-Methyltyramine is a version of the compound L-Tyramine, and it helps encourage your brain to release a bit more norepinephrine, which is the hormone/transmitter that is naturally released, the benefits of N-Methyltyramine can be summarized as:

1.Increases energy and alertness

2.Burns fat

N-Methyl-Tyramine is a Beta Receptor Agonist that can help you burn fat effectively and safely

3.Stimulates your mood

N-methyltyramine may boost the effectiveness of phenylethylamine, Phenylethylamine is a natural mood altering ingredient. This ingredient may help some dieters feel better about dieting.

Chrysin-best aromatase inhibitor

Chrysin

Cas number: 480-40-0

Synonyms: 5,7-Dihydroxyflavone; NP-005901; Galangin flavanone, flavone x

Molecular Formula: C15H10O4

Molecular Weight: 254.24 

What is Chrysin?

Chrysin, from Wikipedia, is a natural, biologically active flavonoid compound extracted from many plant sources, such as passion flowers Passiflora caerulea, propolis, Passiflora incarnata, Honeycomb, etc. Chrysin's chemical name is 5,7-Dihydroxyflavone, and it is a bioflavonoid--the label given to flavonoids when they are used in foods or dietary supplements. Other well-known bioflavonoids are epigallocatechin-3-gallate (EGCG), which is found in green tea, and quercetin, a powerful antioxidant found in red onions and apples.

Chrysin is said to have anti-caner and anxiety-reducing effects in-vitro studies on both human and animals. We are not going to talking about its such functions or benefits here today. However, we are going to explain chrysin as an aromatase inhibitor, or also known as aromatase blocker or Estrogen Blocker.

What is aromatase inhibitors?

Aromatase inhibitors are any synthetic or natural substance that helps to reduce the activity of aromatase; thereby reducing the extent at which testosterone is being converted to estradiol. Aromatase inhibitors are important in certain cancers such as breast and ovarian cancer due to the fact that increased levels of estrogen help the cancer cells to multiply. For men, aromatase inhibitors are often used to prevent or treat gynecomastia (man-boobs or bitch-tits), a common issue with massively increased testosterone levels or increased aromatase activity. Many clinical aromatase inhibitors exist including the famous Arimidex, Teslac and Lentaron, however, there have been several naturally occurring substances which have displayed anti-estrogenic activity, some of which affect the enzyme aromatase. Chrysin is best well-known for its anti-estrogen effects in the bodybuilding supplements.

How does Chrysin work?

There are two major hormones in men and women – these are androgen and estrogen. Androgen is the hormone dominant in males, while estrogen being dominant in females. Estrogen is the primary signal to the pituitary gland in the brain. Depending on your estrogen levels, the pituitary gland will dictate the levels of testosterone produced in the body. The higher the estrogen levels, the lower the amounts of testosterone that is produced.

This is how chrysin benefits you. By cutting down the conversion of testosterone to estrogen, chrysin reduces the levels of estrogen in your body and increases the levels of testosterone.

Benefits of taking chrysin supplements:

1.Raise testosterone levels

Studies show that after the age of 30, a mans testosterone production decreases. If estrogen levels are still normal, they will virtually "turn off" the testosterone production. The higher the level of estrogen, the lower amount of testosterone will be produced. This is why Chrysin is important for blocking the conversion of male hormones into estrogen.

2. Increase Muscle mass.

Studies have shown that supplementing with Chrysin causes testosterone levels to rise, which is extremely important for bodybuilders. The strenuous weight lifting and other endurance activities performed by bodybuilders uses an enormous amount of testosterone, which should be replaced. Testosterone is highly important for the development of muscle mass.

3. Inhibits Cancer Cells

Evidence of inhibiting cancer cell growth suggests the importance of continuous chysin study. Its flavonoids slow the growth of breast carcinoma and human thyroid cancer cell; Chysin may also inhibit the growth of prostate tumor cells.

dosage of Chrysin for bodybuilding supplements

The effective dosage of chrysin supplementation is 1-4 grams per day

Evodiamine extract

Evodiamine extract

English Name: Evodiamine Extract

Chemical Name: Evodia Rutaecarpa

Botanical Source: Evodia rutaecarpa (Juss.)Benth

Synonyms: Wu-Chu-Yu,

Active Ingredients: Evodiamine

Specification: 98% (HPLC)

Part Used and Form: fruit

Appearance: White or pale yellow crystal powder

CAS No: 518-17-2 

Molecular Formula：C₁₉H₁₇N₃O

Characteristic： It has a warm nature and an acrid, bitter, slightly toxic taste, although the fruit is quite fragrant.

What is evodiamine?

Evodiamine is a chemical compound extracted from a particular species of tree, usually known as Evodia trees or Bee Bee Trees found in China, and is said to possess anti-obesity effects along with anti-inflammatory and anti-infectious properties among many others.

Evodiamine is also known as Wu-Chu-Yu, and is used by Chinese herbal specialists as a weight loss supplement. Evodiamine as an ingredient has had increasing interest from the scientific community in the past decade or so. Recently, a review article examined the Evodia species of trees and its major bioactive compounds including Dehydroevodiamine, Evodiamine and Rutaecarpine. The review stated these extracts could prove beneficial for analgesic (pain reducing), cardiovascular and gastrointestinal effects due to its action on CGRP (calcitonin gene-related peptide) release.

Benefits of taking evodiamine extract supplements:

Anti-Obesity and anti-infection. It is useful for those who exercise regularly or at high intensities who may have lowered immune systems, Evodiamine also possesses anti-obesity properties. Recent animal studies have been able to show that Evodiamine has similar thermogenic and stimulatory properties as that of another well known fat loss ingredient; capsaicin.

Anti-cancer. Although evodiamine is primarily used as a weight loss tool, it is also considered to be effective as an inhibitor to cancer. Studies shows taht extracts of evodia fruit strongly inhibit the growth of one specific bacteria (Helicobacter pylori, a bacteria usually treated in mainstream medicine with antibiotics). Unlike conventional antibiotics, the extract did not alter the growth patterns of any other intestinal bacteria. This finding supports the traditional use of evodia fruit in digestive disorders. 

Citrulline Malate

Citrulline Malate

MF: C6H13N3O3C4H6O5

Molecular formula:C6H13N3O3C4H6O5

EINECS No.: 221-678-6

Appearance: White crystal powder

Purity: 98.5%Min.

Synonyms: L-Citrulline Malate, L-Citrulline DL-Malate

What is citrulline malate?

Citrulline malate is a supplement derived from fruits such as watermelons, apples, and other fleshy melons. It is a non essential amino acid in which we do not have an abundance of in the body naturally. Of course to get enough Citrulline and Malate to realize its performance enhancing benefits you would have to eat so many watermelons and apples you would probably get sick, but you see my point. Citrulline Malate has been used with great success by European clinicians who have reported results of increased energy and overall feelings of well-being.

L-Citrulline is an amino acid that supports the body in optimizing blood flow through its conversion to L-arginine and then nitric oxide. Nitric oxide is involved in vasodilatation, and low levels are associated with mental and physical fatigue and sexual dysfunction. Citrulline, which is considered a non-essential amino acid synthesized in the intestinal tract from Glutamine, converts to Arginine in the endothelial cells. This biochemical process involves L-Aspartate and the enzymes Argininosuccinate Synthetase and Argininosuccinate Lyase, in the presence of ATP. Arginine is important for Nitric Oxide production for cardiovascular health; however, most Arginine is utilized in the liver and kidneys, and only a fraction is available for this purpose. Since Citrulline is a precursor to Arginine, it allows for increased and sustained Nitric Oxide production in the endothelium for support of circulatory function.

The benefits of L-Citrulline DL-Malate supplements:

1. Increased Nitric oxide Production

Nitric oxide is the cell-signaling molecule that has a part in regulating blood flow, oxygen delivery, glucose uptake, muscle firepower, and muscle growth. Obviously the ability to control these physiological effects can be of tremendous value to athletes.

2. Reduces Lactic Acid and Ammonia

3. Increases ATP and Phosphocreatine Recovery

No doubt there is a lot to get excited about when it comes to the performance enhancing potential of Citrulline Malate and how it works. Another study showed yet another way Citrulline Malate can benefit athletes - by increasing aerobic energy production.

Studies show subjects using Citrulline Malate have an increase in the rate of muscle ATP (Andenosine Triphosphate, the major energy source within the cell) production during exercise and greater phosphocreatine recovery after exercise.

So taking Citrulline Malate may result in muscles that can keep on going and going... completely smashing the aerobic threshold! These effects are more than likely

Agmatine Sulfate

Agmatine Sulfate

CAS No.: 2482-00-0

Synonyms:(4-Aminobutyl)guanidinium sulphate; 1-Amino-4-guanidinobutane sulfate salt; 4-Guanidinobutylamine sulfate salt; N-(4-Aminobutyl)guanidine sulfate salt

MF: C5H14N4.H2SO4

EINECS No.: 219-617-3

What is Agmatine sulfate?

From Wikipedia, Agmatine is naturally produced in the body from the action of a particular enzyme which transforms L-Arginine to Agmatine. Supplementing with agmatine sulfate does many of the same things that arginine should do, but it seems to be much more effective. Agmatine sulfate has many benefits to the bodybuilder or athlete. The benefits of agmatine sulfate include enhanced muscle pumps, better nutrient partitioning (more calories are shuttled towards muscle tissue and less are stored as fat), and increased production of luteinizing hormone and growth hormone. Agmatine is the new and more effective supplement to increase Nitric Oxide Production. Directly supplementing with Agmatine Sulfate has proven to be much more effective in nutrient transport, partitioning, and enhancing bloodflow than taking Arginine.  Besides the incredible advantages that Agmatine gives you for athletics and performance, supplementing with Agmatine Sulfate has been proven to help with pain prevention and even enhance brain cognition with zero side effects. 

Benefits of taking agmatine sulfate supplements:

1.       Enhance Muscle pumps.

Agmatine sulfate appears to boost muscle pumps in a couple different ways. First, agmatine sulfate may improve nutrient partitioning, leading to more muscle glycogen (carbohydrates stored in muscle tissue) stored and consequently more water retained in the muscle. This can lead to a full look to the muscle and increase muscle pumps. Agmatine has been used for awhile now in the bodybuilding community as a supplement to help in the quest for increased muscle mass. As a potential strong neurotransmitter, it can improve the mind-muscle connection to improve the contractive efforts of our muscles. Stronger, more directed contractions can help promote improved effectiveness of exercises.

2.       Increase nitric oxide production

The nutrient partitioning effects of agmatine may be due to its possible ability to increase the insulin response to carbohydrates, and it may also have something to do with the increased blood flow to the muscle experienced with increased nitric oxide production.

3.       Increase LH and GH level.

Agmatine sulfate may play a role in the hypothalamic control of luteinizing hormone and growth hormone release, leading to increased levels of these hormones. Luteinizing hormone stimulates male Leydig cells to produce testosterone.

4.       Reduce pain. 

In addition, the pain reducing effects of Agmatine can not only be helpful in chronic pain conditions limiting exercise, but may also improve the endurance capacity as pain can often be a limiting factor to performance. Agmatine’s possible ability to regulate insulin production and increase the uptake of glucose may offer benefits for glycogen storage as well as a downgrade in the amount of glucose being transformed into fat.

As a result of these effects, supplementation with agmatine sulfate may improve athletic performance, increase muscle size, fullness, and vascularity, and may also increase fat loss. It may also have a couple of additional benefits like protection against free radical damage and an antidepressant effect. Arginine worked, but agmatine sulfate appears to be an even better option in terms of physique development and performance.

Synmr Industry Ltd is a professional manufacturer and supplier of raw materials for sports nutrition supplement industry; we focus on the latest ingredients that lead the innovative sports brands.

Look forward to your inquiry.

chlorophytum borivilianum extract(Safed Musli)

chlorophytum borivilianum

Synonyms: Safed Musli; C. Borivilianum; Chlorophytum borivilianum root extract

Part used:root

Botanical Name : Chlorophytum Borivilianum

Function:  testosterone booster

What is chlorophytum borivilianum extract ?

From Wikipedia, Chlorophytum borivilianum is a herb with lanceolate leaves, from tropical wet forests in peninsular India. The Hindi name is safed musli.

It is cultivated and eaten as a leaf vegetable in some parts of India, and its roots are used medicinally as a sex tonic under the name safed musli. The medicinal value is thought to derive from its saponin content, up to 17 percent by dry weight. It has also recently been suggested that it may produce an aphrodisiac agent. As medicinal demand has increased, the plant has been brought under cultivation. The saponins and alkaloids present in the plant are the source of its alleged aphrodisiac properties. This herb is used in laddoos for women postpartum.

Its roots are used as a demulcent, a stimulant, diaphoretic, and to help milk production in breast-feeding mothers. They are given balls of the root to chew before and after the birth, so that their milk production will increase. It’s also given to cows for the same purpose.

It is used to cure general debility, in the treatment for diarrhoea and dysentery and as a vitalizer for the whole body. The root powder is fried in ghee (clarified butter) and chewed to get rid of mouth and throat infections. It is also used as a remedy for arthritis and diabetes. It is often an ingredient in paan in India and Pakistan.

It is used as an Allopathic, which means that a disease is treated with remedies which produce effects differing from those produced by the disease, for example antibiotics do this. The word come from the Greek, allosmeaning different or other, and pathos, meaning suffering. The term allopathic or allopath was first used by the man who is regarded as the founding father of homeopathic medicine, Samuel Hahnemann.

It is also given to boost the immune system and modern medical research has borne out this use of it. Chlorophytum borivilianum has immuno-stimulating properties and it has been proved that increases rats’ sperm count after 60 days of being given regular doses of it. The researchers end their discussion with these words “roots of Chlorophytum borivilianum can be useful in the treatment of certain forms of sexual inadequacies, such as premature ejaculation and oligosperma” (R. Kenjale et al 2008 in Phytotherapy Research Vol 22(6)). In other words, rats have benefited from this plant and shown increased sexual activity and increased libido as well as having a “significantly” higher sperm increase. It is believed that this is the Natural Viagra and is now being cultivated on a much larger scale than before so that it can be exported for the benefit of men all around the world. It has been used as a tonic for sexual health by Indians or centuries and they believe it is an aphrodisiac for both sexes.

This plant also has antimicrobial properties, although these are not as efficient as those of the kikar tree, according to other research carried out by Rajesh Dabur et al.

The plant is a rich source of minerals,vitamins, proteins, carbohydrates, steroids and polysaccharides.

It clearly has amazing medical properties and modern medical research is showing once again that the old herbalists knew a thing or two about health giving plants.

Benefits of taking chlorophytum borivilianum supplements

1. Increasing male potency and to fight fatigue.

 It is particularly used for individuals with low sperm count and low libido

2. Energy booster

The roots of the herb are also used to strengthen the general immune system of the body.

3. Growth hormone

 Chlorophytum Borivilianum Root is used to treat impotence and reduced sperm count. There is even mention of an immune-boosting property, but boosting the immune system or sperm production is not the same as boosting growth hormone.

Sulforaphane

Sulforaphane

Synonyms: Broccoli extract, Glucosinolate de Sulforaphane, SFN, Sulforafane, Sulforaphane Glucosinolate, Sulforofano, Sulphoraphane, 1-isothiocayanate-4-methyl-sulfonyl butane

Cas:4478-93-7

Molecular formula: C6H11NOS2

Molecular weight: 177.29

What is Sulforaphane?

Sulforaphane, according to wikipedia, is an organosulfur compound belonging to the family of isothiocyanates, which exhibits anticancer, antidiabetic, and antimicrobial properties.

Where does sulforaphane come from?

Sulforaphane exists in food in its foodbound form known as Glucoraphanin, a glycoside (bound to a sugar) or sulforaphane that is commonly seen as a prodrug or storage form of Sulforaphane. Glucoraphanin is one of a few molecules known as isothiocyanates, existing mostly in cruciferous vegetables alongside Sinigrin (metabolized into Allyl Isothiocyanate), Glucotropaeolin (metabolized into Benzyl Isothiocyanate), Gluconasturtiin (metabolized into Phenethylisothiocyanate) and Glucobrassicin. Sulforaphane is a rather simple organic compound that is found in the largest concentrations in the cruciferous or mustard family of plants, including broccoli, cauliflower, and cabbage. It is a phytochemical, which means it is biologically-activated when the human body breaks its chemical components free of the sugar molecule glucosinolate that it is bound to in plants.

Health benefits of taking sulforaphane supplements:

There are a range of health benefits that the compound brings to the human diet, but chief among them is its ability to act as an antioxidant and bind to free radical oxygen molecules that can cause cellular damage. Because of this activity, it is a natural cancer preventative and has been indicated specifically as being capable of reducing the risk of breast cancer and prostate cancer. These common functions are not what I am going to talk about. Sulforaphane is very popular among the bodybuilding fans and bodybuilders as a sports nutrition supplement, it can mainly be used to

1.Anti-cancer. As mentioned above, sulforaphane can reduce the risk of breast cancer, prostate cancer, and other kinds of cancers.

2.Lose weight

Sulforaphane appears to be able to increase the rate of glycerol release into medium (lipolysis) in a concentration-dependent manner up to 10uM concentration, coupled with an increase in Hormone Sensitive Lipase (HSL) mRNA and CPT1A mRNA (approximately 1.6-fold control) and no effect on Perilipin or ATGL mRNA

3.Build up more muscles

 Italian researchers had discovered that sulforaphane improved the survival chances of one type of stem cell that is capable of developing into muscle cells. 

Sulforaphane dramatically reduced the production of myostatin [MSTN] in the satellite cells

The best natural sources of sulforaphane are fresh broccoli and Brussels sprouts. Tinned cabbage and prepared cabbage in plastic packaging do not contain much sulforaphane. Bodybuilders who want to start experimenting with sulforaphane right away can of course use natural supplements.

Strictly speaking cabbage-type vegetables don't contain sulforaphane, but do contain glucoraphanin. Cutting up, chewing and digesting cabbage-type vegetables converts glucoraphanin into sulforaphane.

Schisandra Chinensis extract

Schisandra Chinensis extract

Synonyms:wu wei zi, Kadsura chinensis,bei wu wei zi,

Kadsura japonica,  Schisandra sphenanthera, Schisandra Berry

Active ingredients: schizandrin (schisandrin, schisandrol A, wuweizichun A)

Specification:Schisandrins 3%-9% , Schisandrin A/B 1%-3% HPLC

Original Plant: Schisandra chinensis ( Turcz.) Baill

Active ingredient: Schisandrins 3%-9%

What is Schisandra Chinensis extract ?

Schizandra Chinensis, according to Wikipedia, gets its name from the fact that its berries possess all five basic flavors: salty, sweet, sour, pungent (spicy), and bitter, sometimes Schizandra, as a Traditional Chinese Medicine belonging to the family of Schisandraceae, is referred to as Chinese Magnolia Vine; It is a deciduous woody vine growing up to 8m long with yellowish-white to pinkish flowers and bears fruits 5-8mm in size and bearing a deep red color.These fruits are where the main bioactive components of Schizandra Chinensis exist, and they are sometimes referred to as Fructus Schizandra. The fruit has a slightly sour taste, and the seeds are more pungent and bitter.

Major chemical composition of Schisaandra Chinensis extract

The major constituents are lignans of biological interest with the dibenzo[ α,c]cyclooctadiene skeleton. Among the approximately 30 lignans are schizandrin (schisandrin, schisandrol A, wuweizichun A, 0.2–0.7%), gomisin A (schisandrol B, wuweizichun B, wuweizi alcohol B, 0.1–3.0%), deoxyschizandrin (deoxyschisandrin, schisandrin A, wuweizisu A, 0.1– 9.0%), (±)-γ-schizandrin (schisandrin B, γ-schisandrin B, wuweizisu B, 0.1–5.0%), and gomisin N (pseudo-γ-schisandrin B, 0.1–0.5%)

As a herbal compound, Shizandra Chinensis (technically Fructus Schizandra) contains:

Schizandrin (actually a mixture of shisandrin, shisandrol A, and wuweizichun A

The lignan Deoxyshizandrin (deoxyschisandrin, schisandrin A, wuweizisu A; totalling 0.1-9% of total weight)

The lignan Gomisin A (schisandrol B, wuweizichun B, and wuweizi alcohol; totalling 0.1-3% of total weight)

The lignan Gomisin N (pseudo-γ-schisandrin B; totalling 0.1-5%)

The lignan γ-Shizandrin (schisandrin B, γ-schisandrin B, wuweizisu B; totalling 0.1–5%)

Benefits of taking Schisandra Chinensis extract  supplements:

Schisandra Chinensis has traditionally been used for treatment of chronic cough and asthma, diabetes, urinary tract disorders and as a general tonic for treating Fatigue associated with illness; The schizandra benefits have been shown in numerous studies. Pharmacological studies have shown that Schisandra is the strongest antioxidant that exists. It increases immune (has similar properties as cordyceps sinensis and hericium erinaceus), endocrine, cardiovascular, gastrointestinal system. Schisandra chinensis lowers sugar and it is proven to enhance physical work capacity and increases stress resistance.

Besides already written benefits as a traditional Chinese Medicine , here are some more schizandra benefits as sports nutrition supplement ingredient:

1.stimulating effect

Schisandra chinensis berry is known for its stimulating effect on the nervous system without the effect of excitement like in amphetamines or caffeine. The higher the degree of exhaustion the greater stimulating effect. Research also shows that schisandra chinensis stimulates the central nervous system

2. Anti-fatigue

laboratory tests show that schisandra berry can improve performance, increase strength and reduce fatigue, also increases stamina and speed and improves concentration. It stimulates the nervous system by increasing the speed of nervous responses, leading to quicker and stronger reflexes.

3. Boosts mental function

studies show that schizandra chinensis can increase mental performance in humans: concentration, fine coordination, sensitivity and endurance in healthy young men. Schizandra has also beneficial effects on eyesight and hearing, increased field of view and improved adaptation to darkness.

4.liver protection

Schisandra Strengthens your Liver and Increases Glutathione Production, and then provide protection against toxins in the liver. Glutathione helps the body get rid of toxins and pollutants