Hordenine hcl

hordenine hcl

Chemical Name: N,N-dimethyl-4-hydroxy-phenethylamine or N,N-dimethyltyramine

CAS number: 6027-23-2

Specification:99%

Synonyms: N,N-dimethyltyramine hcl, hordenine hydrochloride

Molecular Formular: C10H16ClNO

Molecular Weight: 201.69

What is hordenine hcl?

Hordenine, as described in Wikipedia, is a natural alkaloid of the phenethylamine found in many plants, and mostly commonly in barley. Chemically, hordenine is the N-methyl derivative of N-methyltyramine, and the N,N-dimethyl derivative of the well-known biogenic amine tyramine, from which it is biosynthetically derived and with which it shares some pharmacological properties. while hordenine is best known as a central nervous stimulant that assists in weight loss in sports nutriton supplements.

What is the differences between hordenine and hordenine HCL?

There is little difference in application and stability between these two products. The HCL form is more water soluble and more easily absorbed by the body due to its acidic character; thus making it more expensive. In addition, the CAS number of hordenine hcl is 6027-23-2 while CAS number for hordenine is 3595-05-9. Chemically speaking, they are two different products although their propertities are similar. If for hordenine alone, we call it hordenine base.

How does hordenine hcl work?

Hordenine HCl is its ability to inhibit the activity of Monoamine Oxidase B (MAO-B). MAO-B is an enzyme located in the mitochondrial outer membrane. It catalyzes the oxidative deamination of biogenic and xenobiotic amines and plays an important role in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. This enzyme preferentially degrades benzylamine and phenylethylamine. Like MAO-A, MAO-B also degrades dopamine. Usually this degradation function of MAO-B is negative for pre-workout ingredients.

With this MAO-B inhibiting ability, Hordenine HCl may prevent stimulant tolerance by decreasing the effect of monoamine oxidase, thus Hordenine HCl can prevent the breakdown of many stimulants and make them more effective.

Benefits of taking hordenine hcl

Hordenine HCL is used as a stimulant, a stimulant tolerance inhibitor, and for weight loss. Hordenine HCL may assist with weight loss, in part, by encouraging the release of norepinephrine. Norepinephrine is an excitatory hormone and is lipolytic, which means it helps release fat from fat cells that are oxidized, therefore increasing energy and reducing overall fat on the body.  The key benefits of hordenine hcl are sumarrized as below:

1.Enhance energy as a stimulant.

Hordenine hcl, especially when taken with caffeine, has a stimulant effect, helping to provide energy. This could keep you awake longer and aid in concentration in areas where becoming tired too early might be a problem.

2.Lose weight

The increased metabolism efficiency has been known to actually lower some people’s appetites, making weight loss considerably easier. When someone is just less hungry, weight loss is something that just happens as a matter of course.

3. Appetite Control

It can be a difficult feat to keep urges and cravings for various foods under control during a diet or training. The problem is for certain regimens to be successful, sticking as closely as possible to a particular diet can be critical. Having a supplement like Hordenine to help take the edge off of appetite surges can make it much easier to stick to your regimen.

Dosage of Hordenine HCL

Start with 25mg daiy and adjust dosage up or down depending on results. It is common to mix Hordenine with caffeine such as in coffee. This helps extend the effect.

Side Effects of Hordenine hcl

Some possible side effects of hordenine that have been reported are nausea, insomnia, dizziness, anxiety, upset stomach, mood swings, and rapid heart rate.

Plant extract Beta-Ecdysterone 98%HPLC

Plant extract Beta-Ecdysterone 98%HPLC/ Cyanotis Arachnoidea Root Extract

Botanical source: Cyanotis Arachnoidea Extract

CAS: 5289-74-7

Appearance: Light Yellow fine powder / White Crystalline Powder

Part used:root

Synonyms: β-Ecdysone, Cyanotis Extract, Cyanotis Arachnoidea Extract,  ecdysterone, 20-Hydroxyecdysone,  isoinokosterone,

Beta Ecdysterone 95% Cyanotis Extract

What is Beta-Ecdysterone?

Beta ecdysterone , according to wikipedia, also known as ecdisten, ecdysone, isoinokosterone and 20-hydroxyecdysone,  is what is known as a "plant sterol" : a compound found in plants that is structurally similar to anabolic human steroids such as testosterone.  However, beta ecdysterone is a plant sterol; NOT a steroid.

It was first discovered in insects and it was found that they depended upon it for survival. Speculation then arose as to whether the presence of beta ecdysterone in insects played a role in their remarkable body size to strength ratio.

Scientists discovered that ecdysterone could be found occurring naturally in certain herbs (rhaponticum/leuzeae and cyanotis vaga) and eventually developed methods to create high potency extractions.

How does Beta-Ecdysterone work?

Beta Ecdysterone stimulates protein metabolism. Higher levels of protein metabolism will lead to a positive nitrogen balance in your body. Like an air balloon expanding, your muscles will grow. The balloon will not expand without air the same as your muscles won’t grow without protein synthesis. Beta Ecdysterone dramatically increases the synthesis, leaning to significant muscle gain and straight increase.

Benefits of Beta Ecdysterone extract supplement

Beta-ecdysterone also often marketed as a natural alternative to steroids with claims that it's a powerful growth promoter with no negative hormonal consequences. Beta-ecdysterone is used widely by body builders with hopes to build muscle or lean body tissues. The key benefits of Beta-ecdysterone are summarized as below:

1. build lean body mass

 Beta-ecdysterone promotes protein synthesis, which enhances lean body mass when accompanied by resistance training, but the evidence is lacking and inconsistent. Its purpose is to stimulate cellular and muscle recovery so if this actually is true, combining this supplement with high biological value proteins, like animal protein—milk, chicken, eggs, fish—will improve results.

2. Help fat burning

Beta-ecdysterone works by blocking alpha adrenoreceptors. There are a number of feedback mechanisms that prevent the release of norepinephrine (NE), one of the body's primary lipolytic hormones. When NE is released, such as in periods of stress or after taking a sympathomimetic (such as ephedrine), it stimulates both the alpha and beta adrenoreceptors. Stimulation of the beta adrenoreceptors causes the breakdown of fat while stimulating the alpha adrenoreceptors has the opposite effect, preventing the release of NE and lipolysis. Beta-ecdysterone prevents this negative feedback mechanism, thus increasing NErelease and lipolysis.

3. help treat osteoporosis

 Chinese researchers found that beta-ecdysterone treatment alleviated osteoporosis symptoms in mice without any obvious side effects.  Experts concluded that beta-ecdysterone may be a promising candidate drug for the treatment of osteoporosis but more testing is necessary before it can be approved for human treatment.

4. help lower blood glucose levels

In a recent study beta-ecdysterone was found to help lower blood glucose levels—in patients in the normal to moderate blood glucose range—without altering insulin levels. Therefore, it could be of benefit in the treatment of type-II diabetes, and may aid weight loss.

Doasge of Beta-ecdysterone supplement

Studies have shown that supplementation with beta-ecdysterone is safe at dosages of 5 milligrams per kilogram of bodyweight. However, most nutritional companies use significantly lower dosages—about 50-90 mg total. And so many say that athletes would need a much larger dosage than what's included in most nutritional formulas in order to see and muscle growth-related benefits.

Stanford Ingredients Co., Ltd is a professional manufacturer and supplier of Sulbutiamine for the industry of bodybuilding,  dietary supplements, and sports nutriton ingredients. We guarantee you the best raw materials via breaktrough technology and customer service.

Vinpocetine99%- Neuronal Antioxidant as Cognitive ingredient supplement

Vinpocetine99%- Neuronal Antioxidant as Cognitive ingredient supplement

chemical name: ethyl apovincaminate

botanical source: periwinkle plant

Synonyms: Vincamine, Vinca Minor, Periwinkle Extract, Cavinton

CAS No. :42971-09-5

Molecular Formula: C22H26N2O2

Molecular Weight: 350.45

assay:99%min

Appearance: white powder

packing:25kg/drum

What is vinpocetine?

Vinpocetine is an extract from the seeds of the periwinkle plant (Vinca minor), a common, vinelike evergreen ground cover. Vinpocetine is a derivative of the alkaloid vincamine. Like vincamine, it is found in small amounts in the seeds of periwinkle as well as other plants, such as voaconga andCrioceras longiflorus. Throughout the world, vincamine has been used to treat senile dementia with significant success. Studies have found vinpocetine to demonstrate many of the same functions as those of vincamine, but without the side effects.

There are actually over 50 alkaloids presents in the Vinca Minor, of which vinpocetine is thought to be the superior and most researched compound, due to low its low toxicity and reported benefits. Additionally, it is reported to be better than vincamine at improving memory and circulation in the brain.

How does vinpocetine work?

Numerous scientific studies have shown vinpocetine to be of benefit for the prevention and improvement of many different kinds of ailments. It enhances cognitive functions, including those involving long- and short-term memory, and it has also been shown to be valuable in protecting heart, visual, and hearing functions, among other benefits.

In broadest terms, vinpocetine is a powerful memory enhancer. It achieves this principally by facilitating cerebral metabolism and improving blood flow in the brain. It works by causing mild dilation of blood vessels, thereby allowing for increased cerebral blood flow, which results in increased oxygenation and glucose utilization.

This makes vinpocetine an ideal candidate not only for the improvement and prevention of certain disease processes in need of increased blood flow and oxygenation, but also for athletes who want to enhance their performance by increasing brain oxygenation, such as skiers, mountain climbers, and high-altitude hikers.

Benefits of taking vinpocetine supplement

1.Improves Memory

The main purpose of vinpocetine is to enhance memory and cognition. It also improves awareness and alertness. People who suffer short as well as long-term memory loss can benefit from vinpocetine. What does vinpocetine exactly do to overcome memory loss? Well, it increases dilation of blood vessels, promotes blood circulation in the brain, and improves oxygen usage.

2. Treats Hair loss

Since vinpocetine is a natural cerebral vasodilator, it can be highly effective for treating hair loss. If you are experiencing hair loss since a very long time, you should begin using vinpocetine. It can offer better protection to your hair without any side-effects unlike other chemical treatments.

3. Improves Cognition

Again, as vinpocetine is excellent in blood circulation in the brain, it makes a great contribution in improving the cognitive function, especially for people in advanced age groups. It enhances neuronal plasticity which has been reported to be a spatial memory booster in animal models while improving cognitive performance in human beings.

Dosage of Vinpocetine

Although vinpocetine is the best medicine for boosting memory and concentration, it should always be consumed after doctor's consultation and in correct dosage. It is recommended to consume vinpocetine more than once daily however, some people may be sensitive to such a dose. it is better to consume a 5mg vinpocetine for the first time and look for any allergic reactions by your body or other negative responses. By doing this you can prevent possible side-effects of vinpocetine. Then you can move on to 10 mg dosage once you are familiar with 5mg dosage.

Stanford Ingredients Co., Ltd is a professional manufacturer and supplier of Vinpocetine for the industry of bodybuilding,  dietary supplements, and sports nutriton ingredients. We guarantee you the best raw materials via breaktrough technology and customer service.

bacopa monnieri extract 20% Bacopaside Chinese herbal nootropics

bacopa monnieri extract 20% Bacopaside Chinese herbal nootropics

Latin Name: Bacopa monnieri (L.) Wettst.

Synonyms: baocopa extract, Brahmi, Aindri, Lysimachia monnieri L. Cent., Graticola monnieri L., Herpestis monniera L. Kunth., Water hyssop, Thyme-leafed gratiola, Indian Pennywort

Specification: Bacopaside 20%~50% HPLC

Appearance: Yellow brown fine powder

CAS No.: 382146-66-9

What is bacopa monnieri extract?

Bacopa monnieri extract, according to Wikipedia, is an herb native to India that has a long history of use in the Ayurvedic system of medicine where it is known as Brahmi. Bacopa monnieri is one of the most important herbs in India and is used for a wide variety of ailments and as a general tonic and an anti-aging herb. In the west, Bacopa monnieri is gaining popularity due to recent studies that examine its effect on the brain, cancer and it ability to keep stress at bay. There are many other names for bacopa monnieri extract,such as  water hyssop, water purslane , Bacopa monnieri (L.) Wettst ,Brahmi, etc. Brahmi is also the name given to Centella asiatica, particularly in North India.

What are in the bacopa monnieri extract

From wikipedia, Bacopa monnieri has many chemical constituents It contains saponins, designated as bacopaside I, II, III, IV and V. Additional phytochemicals betulinic acid, wogonin and oroxindin have been isolated from the aerial parts. This herb also has the flavonoids luteolin and apigenin. Dammarane-type triterpenoid saponins classified as pseudojujubogenin and jujubogenin glycosides are reported as some of the active components in this plant. Bacoside A, the bioactive component of this Indian medicinal plant is a mixture of saponins with bacoside A3, bacopaside II, jujubogenin isomer of bacopasaponin C and bacopasaponin C as major constituents.

Benefits of taking Bacopa monnieri extract

Bacopa monnieri extract is considered to be a nerve and brain tonic in Ayurvedic and Chinese medicine and is used to treat epilepsy, sexual dysfunction and fertility problems. Bacopa monnieri may be helpful in treating memory problems and depression in the elderly. Some key benefits of bacopa are sumarrized as below:

1.Enhance memory.

 Bacopa monnieri extract has many Cognitive Functions known as a brain tonic because it can be used to improve learning problems, memory, and concentration.

2.Enhance mood and reduce anxiety

Bacopa monnieri supports the effects of certain neurotransmitters, including serotonin and acetylcholine, states the University of Michigan Health System. This effect on neurotransmitters is what enables Bacopa monnieri to support mood-related symptoms. According toDrug Digest, animal studies of Bacopa monnieri’s effectiveness in treating mood issues have produced positive results, finding that Bacopa monnieri was nearly as effective as common prescription anti-anxiety medications, but without the side effects.

3. Cancer Prevention and Treatment

 Bacopa has long been used in the treatment of cancer in Ayurvedic medicine.

SIDE EFFECTS OF BACOPA MONNIERI

Long term side effects and safety of bacopa monnieri extract are currently not fully known. As with most herbs, it's best to take breaks from use.

Dosage of Bacopa monnieri extract supplement

There is no specified dosage for Bacopa monnieri. Some companies suggest 100mg daily but some supplement brands suggest 2 tablets of 225mg twice daily.Therefore, There is no right dosage that applies to everyone, each person is unique. In general use the lowest dosage that works. The usual dosage is 100 mg to 300 mg of the extract once or twice daily. It appears that it works better when taken a few days in a row rather than just once.

Stanford Ingredients Co., Ltd is a professional manufacturer and supplier of Bacopa monnieri extract for the industry of bodybuilding,  dietary supplements, and sports nutriton ingredients. We guarantee you the best raw materials via breaktrough technology and customer service.

Noopept

Noopept 99%

CAS: 157115-85-0

Chemical name: N-(1-(Phenylacetyl)-L-prolyl)glycine ethyl ester

Synonyms: Ноопепт,Noopeptide,GVS-111, N-phenylacetyl-L-prolylglycine ethyl ester

Molecular Formula: C17H22N2O4

Molecular Weight: 318.37

Appearance:White or colourless crystalline powder

What is noopept?

Noopept is a nootropic compound that was first discovered in Russia. It has shown to be 1000 times more potent than Piracetam, the most popular of the racetam family. On a structural basis, Noopept is a dipeptide conjugate of Piracetam. According to Wikipedia, Noopept has many other names such as Ноопепт; GVS-111, N-phenylacetyl-L-prolylglycine ethyl ester. In research, Noopept has displayed significant neuroprotective properties. It has also been shown to enhance the activity of the immune system in both healthy and immune-compromised animals.

How does noopept work?

 Noopept works on the AMPA and NDMA rector sites and their pathways of function. It also has an affinity with the Acetylcholine system and the ACh receptor sites. Both of these factors contribute to Noopept’s array of nootropic benefits.

Like Aniracetam, Noopept seems to stimulate an anxiolytic response in animal and human models. This is not a guaranteed result and seems to vary widely between subjects. Like with Aniracetam, Noopept seems stimulate Dopamine receptor sites (D2 and D3) as well as the ACh nicotinic receptor sites. Noopept also seems to stimulate certain Serotonin receptors and this may also lead to mood boosting qualities.

Benefits of taking noopept supplement

Noopept is commonly prescribed as a general nootropic in many countries and a Cognitive Health Supplement ingreidnets uesd in sports nutrition. Its key benefits are summarized as below:

1.Improves Memory and Learning

Noopept’s most emphasized benefit is how it can enhance memory and improve the learning process. Noopept, like Piracetam, assists with memory formation, but with additional benefits not present in the latter, which are memory consolidation and memory retrieval. Noopept facilitates the proper management of all forms of stimuli as they are processed by the brain, which allows for better retrieval of memory. In other words, signals being processed by our senses are more streamlined as they are transported into our brains in the form of memory.

2.Boost Mood

It can reduced anxiety and depression Symptoms,thus improve mood.

3.Treatment of Alzheimer's disease

Studies show that Noopept has high neuroprotective properties. The stimulation of the neurons caused by the health supplement prevents oxidative damage and apoptosis in the human brain. Many patients dealing with cognitive impairment regularly can benefit from a regular dosage of Noopept to prevent further dissociative cognitive functions.

Dosages of noopept supplement

The recommended dose of this supplement is between 10-20 mg daily. This can be taken in divided doses throughout the day, as desired. It is recommended to start on the low side and adjust as needed. Since this is a powder, having a good milligram scale is essential.

Sulbutiamine- nootropic

Sulbutiamine

CAS No.: 3286-46-2

Synonyms: Arcalion, Enerion, Bisibuthiamine, Youvitan

Molecular Formula:C32H46N8O6S2

Molecular Weight: 702.89

What is Sulbutiamine?

Sulbutiamine, accordingto wikipedia, as a synthetic derivative of thiamine (vitamin B1), it is a lipophilic compound that crosses the blood–brain barrier more readily than thiamine and increases the levels of thiamine and thiamine phosphate esters in the brain.

Does Sulbutiamine work?

Sulbutiamine, similar to coffee, easily crosses a person's blood brain barrier. This enables these two drugs to contact your mind and produce an extremely apparent effect. Both of these supplements then impact quantities/effects of distinct neurotransmitters in your brain. Neurotransmitters are the brain's manner of interacting with itself. Theoretically, in the event that an individual had zero neurotransmitters, you would be wholly brain dead.

Caffeine minimizes the effects involving the neurotransmitter adenosine. Because adenosine helps bring about sleep and inhibits alertness, caffeine will give you a rush of energy. Nonetheless, it won't affect the numbers of adenosine, it merely keeps their effects in check. While the caffeine wears away, the adenosine begins to be effective yet again, and you will most certainly crash.

Sulbutiamine effects absolutely different neurotransmitters. It raises amounts of ACh, GABA, and Glutamate. GABA improves mood plus reduces stress and anxiety. Glutamate and ACh work together to improve a person's memory and decrease levels of fatigue.

Benefits of taking Sulbutiamine supplement:

Sulbutiamine is a nootropic designed to give you more energy, improve your mood, and boost your memory.  The detailed benefits are summarized as below:

1.boost more energy

Sulbutiamine’s nootropic properties boost both physical and mental levels in the body leaving you with a feeling of high energy. It is used primarily to treat a condition called asthenia and fatigue.

2.improve mood

Sulbutiamine is another great nootropic to help with mood. Some people have compared Sulbutiamine to MDMA’s anxiolytic and anti-depressant qualities without the amphetamine stimulation. This is a rather bold statement but is likely proof that this B1 Vitamin derived nootropic may have some great mood boosting qualities. Sulbutimaine defiantly works for some and has been prescribed in countries outside North America to help with depression.

Sulbutiamine’s effects on mood are likely related to effects it has on dopamine. This nootropic increases dopamine and dopamine (D1) receptor density in the prefrontal cortex. Dopamine transmission problems are often a cause of depression. This would explain Sulbutiamines’ effects on possible mood improvement. It was also seen in a study to reduce behavioural inhibitions which are commonly seen in peoples with shyness and depression.

3.boost memory

Also from wikipeidia reference citation, Several studies have shown that sulbutiamine improves memory through the potentiation of cholinergic, dopaminergic, and glutamatergic transmission. When sulbutiamine is administered to mice, they perform better on operant conditioning tests[14] and object recognition tests.[15] Sulbutiamine also reduces the amnesiac effects of dizocilpine and improves memory in schizophrenics.

4. Erectile dysfunction

According to one recent study, sulbutiamine is effective for the treatment of psychogenic erectile dysfunction.

Sulbutiamine Dosage

The recommended Sulbutiamine dosage is usually 600 mg per day, taken in three 200 mg doses, one in the morning and one in the afternoon and another in the evening. It is sold in tablet capsule and powder form, generally in doses 200 mg each.

3,3′-Diindolylmethane(DIM)

3,3′-Diindolylmethane

Molecular Formula: C17H14N2 
Molecular weight: 246.31 
CAS#: 1968-05-4 

Appearance: Off- white to white crystalline powder

Synonyms:DIM, Diindolylmethane, Diindolyl methane;Diindolymetano

What is 3,3′-Diindolylmethane?

3,3′-Diindolylmethane, from Wikipedia description, also commonly known as DIM, is a natural substance produced when the body breaks down indole-3-carbinol, a compound found in the following vegetables:broccoli, Brussel sprouts, cabbage, cauliflower, collard greens, kale, mustard greens, watercress,etc.

How Does 3,3′-Diindolylmethane Work?

3,3′-Diindolylmethane stimulates more efficient estrogen metabolism. Supplementing the diet with DIM and eating cruciferous vegetables increases the specific aerobic metabolism for estrogen, multiplying the chance for estrogen to be broken down into its beneficial, or "good" estrogen metabolites. These "good"estrogen metabolites are known as the 2-hydroxy estrogens. Many of the benefits that are attributed to estrogen, which include its ability to protect the heart and brain with its antioxidant activity, are now known to come from these "good" metabolites.

When 3,3′-Diindolylmethane(DIM) increases the "good" estrogen metabolites, there is a simultaneous reduction in the levels of undesirable or "bad" estrogen metabolites. These include the 16-hydroxy estrogens, which are not antioxidants and can actually cause cancer. Greater production of these "bad" estrogen metabolites is promoted by obesity and exposure to a number of manmade environmental chemicals. These "bad" estrogen metabolites are responsible for many of estrogen's undesirable actions in women and men, including further unwanted weight gain, breast cancer, and uterine cancer.

In addition, a slow metabolism of estrogen, which leaves too much unmetabolized active estrogen known as estradiol in the body, can be a problem for both women and men. Elevated estradiol causes moodiness and breast pain in women and loss of sex drive in men. By promoting a healthy estrogen metabolism, DIM adjusts the balance of estradiol to its "good" metabolites. This also can result in a more desirable action fro testosterone. Testosterone supports energy and mood and helps sustain interest in sex in both men and women. When supplemental DIM is taken along with a program of regular exercise, it can help estrogen and testosterone contribute to good physical conditioning.

Benefits of taking 3,3′-Diindolylmethane(DIM) supplement

1. Estrogen Metabolism

Taking Diindolylmethane supplements increases the efficiency of the metabolic processing of estrogen. This increase in efficiency has been linked to increased antioxidant protection of the heart and brain. This process is also responsible for other benefits, such as an increase in libido in men and women and a decrease in moodiness for women.

2. Hormonal Balance

Diindolylmethane also appears to promote a healthy balance of testosterone in the body. Testosterone supports energy, promotes a happy mood and helps to maintain a healthy sex drive. In addition, Zeligs states that DIM may have an anti-aging effect and may help encourage lean body mass. When combined with exercise, it can increase muscle mass. These benefits are speculative, however, and more research needs to be done to confirm the efficacy of these claims.

3. Anticancer Benefits

According to Memorial Sloan-Kettering Cancer Center, DIM has been found to help prevent and treat breast and prostate cancers. Studies done on animals also found DIM to prevent the replication and spreading of cancer cells. Exactly how DIM helps to prevent and treat cancer is unknown; however, DIM inhibits angiogenesis, which is the formation of new blood vessels. Tumors require the growth of new blood vessels to supply the nourishment that is necessary for tumors to thrive. By preventing the growth of new blood vessels, DIM may therefore help to abolish tumors. Unfortunately, only a few small studies have been done on DIM so far, and more research needs to be done to confirm the usefulness of DIM as an anticancer supplement.