Thursday, March 21, 2013

Citrulline Malate


Citrulline Malate
MF: C6H13N3O3C4H6O5
Molecular formula:C6H13N3O3C4H6O5
EINECS No.: 221-678-6
Appearance: White crystal powder
Purity: 98.5%Min.
Synonyms: L-Citrulline Malate, L-Citrulline DL-Malate

What is citrulline malate?
Citrulline malate is a supplement derived from fruits such as watermelons, apples, and other fleshy melons. It is a non essential amino acid in which we do not have an abundance of in the body naturally. Of course to get enough Citrulline and Malate to realize its performance enhancing benefits you would have to eat so many watermelons and apples you would probably get sick, but you see my point. Citrulline Malate has been used with great success by European clinicians who have reported results of increased energy and overall feelings of well-being.

L-Citrulline is an amino acid that supports the body in optimizing blood flow through its conversion to L-arginine and then nitric oxide. Nitric oxide is involved in vasodilatation, and low levels are associated with mental and physical fatigue and sexual dysfunction. Citrulline, which is considered a non-essential amino acid synthesized in the intestinal tract from Glutamine, converts to Arginine in the endothelial cells. This biochemical process involves L-Aspartate and the enzymes Argininosuccinate Synthetase and Argininosuccinate Lyase, in the presence of ATP. Arginine is important for Nitric Oxide production for cardiovascular health; however, most Arginine is utilized in the liver and kidneys, and only a fraction is available for this purpose. Since Citrulline is a precursor to Arginine, it allows for increased and sustained Nitric Oxide production in the endothelium for support of circulatory function.

The benefits of L-Citrulline DL-Malate supplements:
1. Increased Nitric oxide Production
Nitric oxide is the cell-signaling molecule that has a part in regulating blood flow, oxygen delivery, glucose uptake, muscle firepower, and muscle growth. Obviously the ability to control these physiological effects can be of tremendous value to athletes.
2. Reduces Lactic Acid and Ammonia
3. Increases ATP and Phosphocreatine Recovery
No doubt there is a lot to get excited about when it comes to the performance enhancing potential of Citrulline Malate and how it works. Another study showed yet another way Citrulline Malate can benefit athletes - by increasing aerobic energy production.

Studies show subjects using Citrulline Malate have an increase in the rate of muscle ATP (Andenosine Triphosphate, the major energy source within the cell) production during exercise and greater phosphocreatine recovery after exercise.

So taking Citrulline Malate may result in muscles that can keep on going and going... completely smashing the aerobic threshold! These effects are more than likely

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