Thursday, December 27, 2012

3,4-divanillyltetrahydrofuran

3,4-divanillyltetrahydrofuran (nettle root extract)
Botanical source: Nettle Root Extract
CAS Number: 34730‐78‐4
Molecular Formula: C20H24O5
Molecular Weight: 344.4016
Testing Method: HPLC
Synonyms: nettle root extract; Stinging Nettle Extract; Urtica Dioica root;
Appearance: Brown powder
Specification: 50%, 80%, 95%, 98%
Package: 25kg/drum


What is 3,4-divanillyltetrahydrofuran?

3,4-divanillyltetrahydrofuran is extracted from Urtica Diodica, or more commonly referred as stinging nettle root. 3,4-divanillyltetrahydrofuran is typically called stinging nettle, because chemicals in the hairs or spines on the leaves and stems cause skin irritation and pain when touched. It has many other names, such as nettle root extract, Stinging Nettle Extract, Urtica Dioica root. 3,4-divanillyltetrahydrofuran is a competitive inhibitor and therefore competes with testosterone at the binding site.  Since 3,4-D is also a more potent ligand for the SHBG binding site it binds stronger and for a longer amount of time, increasing the likelihood that it will become bound and prevent a testosterone molecule from becoming bound.


Another paradoxical process of interest in relation to 3,4-D is that in response to increasing levels of testosterone SHBG levels are actually decreased causing a positive feedback loop that leads to a greater percentage of inhibition given the same dosage.


How does 3,4-divanillyltetrahydrofuran work?

3,4-divanillyltetrahydrofuran primarily works by attaching to the sex hormone-binding globulin (SHBG). What SHBG does is bind to your sex hormones; mostly testosterone and estradiol. So the basic function of SHBG is to regulate the amount of biologically active hormones in your body. The reasons for this are unclear, however I'm guessing it is because your body loves equilibrium. Anyways, now that we know what SHBG is we can understand how 3,4-Divanillytetrahydrofuran works. It attaches to SHBG thus rendering it inactive so it is then unable to bind to your sex hormones. This in theory will allow your free testosterone and estradiol to rise, and we know higher testosterone promotes muscle growth.

Benefits of taking 3,4-divanillyltetrahydrofuran supplements
Using a supplement which contains 3 4-divanillyltetrahydrofuran can have a significant impact on your progress as an athlete, potentially improving your physique. This ingredient is in fact a natural nettle root extract, which is found in China. Discover how 3, 4-divanillyltetrahydrofuran accelerate your progress, the pitfalls of this plant extract and how it works.

1. increase free testosterone
The key benefit of 3 4-divanillyltetrahydrofuran is the fact that it can increase your ‘free testosterone’ levels. As a result you have the potential to be a lot more anabolic. As you may know, this means that you are able to assimilate much more protein throughout the day due to an increase in your protein synthesis levels. As a result, you can expect to gain extra muscle mass, increase your strength levels and even lose body fat.

2. Achieve larger muscle mass and strength
3,4-Divanillyltetrahydrofuran is a very popular ingredient in bodybuilding supplements because of its ability to keep testosterone flowing freely through the body. Since testosterone is concentrated in the muscle tissue, 3,4-Divanillyltetrahydrofuran helps to increase the free flowing beneficial testosterone, which means an increase in lean muscle mass.


As a potent testosterone booster, 3,4-Divanillyltetrahydrofuran also performs other functions that could be helpful to bodybuilders. One journal found that 3,4-Divanillyltetrahydrofuran did have glucose lowering abilities, or that it is anti-hyperglycemic. Additionally, another journal stated that the glucose lowering abilities came from it causing increased insulin secretion in the Langerhance Isletes (these are the cells that produce hormones in the pancreas). This research seems to indicate that stinging nettle could be used manipulate insulin as well.

Stanford Ingredients Co., Ltd is a professional manufacturer and supplier of raw materials for sports nutrition industries.  3,4-divanillyltetrahydrofuran is one of very competitive products. If you have any inquiry about 3,4-divanillyltetrahydrofuran, do not hesitate to let us know.

Best regards 

Stanford Lee

Stanford Ingredients Co., Ltd

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