3,4-divanillyltetrahydrofuran

3,4-divanillyltetrahydrofuran (nettle root extract)
Botanical source: Nettle Root Extract
CAS Number: 34730‐78‐4
Molecular Formula: C20H24O5
Molecular Weight: 344.4016
Testing Method: HPLC
Synonyms: nettle root extract; Stinging Nettle Extract; Urtica Dioica root;
Appearance: Brown powder
Specification: 50%, 80%, 95%, 98%
Package: 25kg/drum

What is 3,4-divanillyltetrahydrofuran?

3,4-divanillyltetrahydrofuran is extracted from Urtica Diodica, or more commonly referred as stinging nettle root. 3,4-divanillyltetrahydrofuran is typically called stinging nettle, because chemicals in the hairs or spines on the leaves and stems cause skin irritation and pain when touched. It has many other names, such as nettle root extract, Stinging Nettle Extract, Urtica Dioica root. 3,4-divanillyltetrahydrofuran is a competitive inhibitor and therefore competes with testosterone at the binding site.  Since 3,4-D is also a more potent ligand for the SHBG binding site it binds stronger and for a longer amount of time, increasing the likelihood that it will become bound and prevent a testosterone molecule from becoming bound.

Another paradoxical process of interest in relation to 3,4-D is that in response to increasing levels of testosterone SHBG levels are actually decreased causing a positive feedback loop that leads to a greater percentage of inhibition given the same dosage.

How does 3,4-divanillyltetrahydrofuran work?

3,4-divanillyltetrahydrofuran primarily works by attaching to the sex hormone-binding globulin (SHBG). What SHBG does is bind to your sex hormones; mostly testosterone and estradiol. So the basic function of SHBG is to regulate the amount of biologically active hormones in your body. The reasons for this are unclear, however I'm guessing it is because your body loves equilibrium. Anyways, now that we know what SHBG is we can understand how 3,4-Divanillytetrahydrofuran works. It attaches to SHBG thus rendering it inactive so it is then unable to bind to your sex hormones. This in theory will allow your free testosterone and estradiol to rise, and we know higher testosterone promotes muscle growth.

Benefits of taking 3,4-divanillyltetrahydrofuran supplements

Using a supplement which contains 3 4-divanillyltetrahydrofuran can have a significant impact on your progress as an athlete, potentially improving your physique. This ingredient is in fact a natural nettle root extract, which is found in China. Discover how 3, 4-divanillyltetrahydrofuran accelerate your progress, the pitfalls of this plant extract and how it works.

1. increase free testosterone

The key benefit of 3 4-divanillyltetrahydrofuran is the fact that it can increase your ‘free testosterone’ levels. As a result you have the potential to be a lot more anabolic. As you may know, this means that you are able to assimilate much more protein throughout the day due to an increase in your protein synthesis levels. As a result, you can expect to gain extra muscle mass, increase your strength levels and even lose body fat.

2. Achieve larger muscle mass and strength

3,4-Divanillyltetrahydrofuran is a very popular ingredient in bodybuilding supplements because of its ability to keep testosterone flowing freely through the body. Since testosterone is concentrated in the muscle tissue, 3,4-Divanillyltetrahydrofuran helps to increase the free flowing beneficial testosterone, which means an increase in lean muscle mass.

As a potent testosterone booster, 3,4-Divanillyltetrahydrofuran also performs other functions that could be helpful to bodybuilders. One journal found that 3,4-Divanillyltetrahydrofuran did have glucose lowering abilities, or that it is anti-hyperglycemic. Additionally, another journal stated that the glucose lowering abilities came from it causing increased insulin secretion in the Langerhance Isletes (these are the cells that produce hormones in the pancreas). This research seems to indicate that stinging nettle could be used manipulate insulin as well.

Stanford Ingredients Co., Ltd is a professional manufacturer and supplier of raw materials for sports nutrition industries.  3,4-divanillyltetrahydrofuran is one of very competitive products. If you have any inquiry about 3,4-divanillyltetrahydrofuran, do not hesitate to let us know.

Best regards 

Stanford Lee

Stanford Ingredients Co., Ltd

What is the Difference between yohimbine and alpha yohimbine(rauwolscine)?

Alpha yohimbine are alkaloid central nervous system stimulants found in Indian snakeroot and bark. As herbs, they act by blocking alpha-adrenoceptors and are generally taken as fat loss helps, mood enhancers and power boosters. Nevertheless, there are numerous variations that are essential to consider when selecting which to make use o

Yohimbine.

Yohimbine (or Yohimbine HCL) is an extract of yohimbe tree bark that functions mainly on alpha-2 adrenoceptors. The event of those receptors is to maintain fat saved within the body. They're extremely concentrated precisely where you had anticipate them to be -- within the abdominal region of males and around the buttocks and thighs of girls. The alpha - 2 receptors and increases blood flow is blocked by yohimbine to fat tissues, letting the fat to be released easily and burned away. Obstructing the alpha-2 receptors also results in the launch of norepinephrine, which has an energy increase and converts fat in to heat. Epinephrine and norepinephrine release are also in charge of the side - effects occasionally connected with yohimbine, such as sleeplessness, anxiety, and changes in blood stress.

Yohimbine is a 5-HT1A/B receptor agonist, meaning it stimulates serotonergic activity and elevates mood, much like an anti-depressant. In addition, both its affect on norepinephrine and its inhibition of monoamine oxidase, mimic actions identified in anti-depressants, especially MAOIs. Study shows that it's a good addition to some anti-depressant treatments, improving the aftereffect of drugs like Prozac.

Alpha Yohimbine.

Alpha yohimbine, also recognized as rauwolscine, is a stereoisomer of yohimbine, meaning that it has the same chemical qualities as yohimbine, but the atoms within it are organized differently. Some significant differences are created by this alternate arrangement, even as the results stay the same.

Alpha yohimbine is more very concentrated on alpha-2 receptors than alpha-1 receptors, as much as 50 times more than standard yohimbine. Since the alpha-2 receptors are responsible for fat storage and the alpha-1 receptors have a job in adrenaline production, this change in focus equals more targeted yohimbe fat reduction with less stimulant effects.

You will find differences in the way alpha yohimbine functions on alpha-2 receptors also. It's more particular for alpha-2b and alpha-2c receptors than for alpha-2a receptors. This translates to a level better lessening of side-effects like raised cortisol, increased heartbeat, and jitters, while also raising the quantity of dopamine relative to norepinephrine. The outcome is that, as well as stimulating fat loss, alpha yohimbine increases determination and concentrate and has an energy increase, all with small or no side - effects.

Alpha yohimbine's effect on disposition is comparable to yohimbine. They both act on serotonin receptors, but alpha yohimbine is somewhat more powerful.

Which is appropriate for you?

Both alpha and yohimbine yohimbine are superb fat burners that boost power and elevate mood. Possibly one is a great option within a significant weight-loss program. When considering which to purchase, note that yohimbine is the correct and attempted nutritional supplement. It has been studied more completely and there's a larger quantity of information on its use, particularly amongst body-builders and athletes.

Alpha yohimbine is a great pick for anyone who find stimulant effects uncomfortable or favor the added advantage of improved motivation. However, alpha yohimbine comes with a cost. It is around five times more costly than it is likewise named cousin.

From the introduction of OxyElite Pro of USP Labs ,we know that:

Rauwolfia Canescens (Rauwolscine)

This super ingredient is suggested to block and shut down the Alpha-2 receptor.


Rauwolscine is related to yohimbine, a popular ingredient found in many thermogenic products due to its ability to work against (antagonize) Alpha 2-receptors.


But there's a BIG problem with yohimbine. Not only does it work against the Alpha 2-receptors, it also works against the Alpha 1-receptors. And that's not good because a compound that works against the Alpha 1-receptors may actually inhibit fat loss.


So the same compound that may help improve fat breakdown, may also prevent fat breakdown too. It's kind of like taking one step forward, and one step back, or hitting the gas pedal and breaks on a car at the same time. The end result to you is a small if barely noticeable affect on fat loss, which is what's suggested in some of the literature with yohimbine use (14-17).


And this is why Rauwolscine is included in the OxyELITE Pro line up. It may be equally effective as yohimbine at working against your Alpha 2-receptors (great for fat loss), while having minimal effect on your Alpha 1-receptors (even better for fat loss)!


Stanford Ingredients Co., Ltd is a professional manufacturer of raw materials for sports nutritrion.


Stocks for alpha yohimbine are available.

Higenamine hcl-stimulant and weight loss ingredient replacement for 1,3dimethylamylamine hcl

Chemical name: Higenamine hcl CAS #: 5843-65-2 Molecular formula: C16H17NO3 Molecular Weight: 271.12 Synonyms:Higenamine, norcoclaurine, demethyl coclaurine,DL-Demethylcoclaurine                    Specifications: 98%min

What is Higenamine hcl

Higenamine hcl, commonly known as demethyl coclaurine, and norcoclaurine in chemical field. From wikipedia, higenamine is defined as a chemical compound found in a variety of plants including Nandina domestica, Aconitum carmichaelii, Asarum heterotropioides, Galium divaricatum, Annona squamosa, and Nelumbo nucifera (lotus seeds). Higenamine has a long history of use in traditional medicine in ancient China. Historically, the plants that higenamine comes from have been used to treat breathing disorders and cough through these receptors.

Why Higenamine hcl is so hot recently?

Higenamine hcl is known as an ideal DMAA substitute in sports nutrition supplement industry. DMAA, also called 1,3 dimethylamylamine，is a central nervous system stimulant, mainly used in preworkout supplement and weight loss ingredients. According to the FDA, there have been too many public complaints about products containing DMAA, and even people died. DMAA is said to be synthetic and harmful to human body as a dietary supplement. That’s why higenamine hcl is now many supplement formulas of the branded finished products. The sports nutrition manufacturers just want to replace the DMAA. Therfore, is higenamine hcl powerful enough?

Health Benefits of Higenamine hcl

Higenamine works as a stimulant to help increase focus and mental clarity. As many of you know, many stimulants tend to restrict the veins causing them to inhibit the production of Nitric Oxide. Some research is showing that higenamine doesn’t affect nitric oxide production like other stimulants. This is really an amazing break through for lifters and explosive athletes. Imagine a product where you can get the most out of your Nitric Oxide supplement and still get stimulating energy, this is what Norcoclaurine is starting to do. The functions of higenamine hcl are summarized as:

1.    Increase focus and mental clarity.(as a stimulant with no restriction of the veins)

2.    Function as a fat burner. Higenamine is a molecule that is part of the Nandina plant that has traditionally been used as an anti-asthmatic. Since Ephedrine and its fat burning mechanism are also anti-asthmatic, Higenamine might be a fat burner. Higenamine is a catecholamine-like structure that interacts with the same class of receptors that the fat burners Synephrine and Ephedrine do.

3. Interactions with Sexuality. higenamine appears to induce relaxation and promote erection through beta-adrenergic interactions.The inhibition of NO was seen as an injection of 10mg/kg bodyweight, a large dose.

Stanford Ingredients Co., Ltd is one of the manufacturers of DMAA in China, and we are now focusing on the latest raw ingredients for sports nutrition industry. Higenamine hcl with specifications 98%, 99% are available in our stock.

Dendrobium extract-a natural stimulant replacement for DMAA(1,3 dimethylamylamine hcl

English name: Dendrobium Nobile Extract
Synonyms:Shi Hu, Dendrobium nobile Lindl, Herba Dendrobii
Used Part: Dried stem
Specifications: 5:1, 10:1,1%,5%,20%
Main active ingredients: Dendrobine, Dendroxine, Dendramine, nobilonine, 6-hybroxydendrobine, B-Phenylethylamine, N,N-Dimethyl-B-Phenylethylamine,

What is Dendrobium Extract?

Dendrobium extract, also named dendrobium nobile exract, Shi Hu in Chinese, has been used as a traditional herb medicine in China for more than 1300 years. From wikipedia,There are many dendrobium species available, such as dendrobium nobile Lindl, dendrobium candidum, dendrobium officinale, dendrobium huoshanense, and dendrobium devonianum Paxt. However, among these species, dendrobium nobile is the most common and popular extract.

Why dendrobium extracts are so hot recently? 

Dendrobium extract is known as DMAA substitute in sports nutrition supplement industry. DMAA, also called 1,3dimethylamylamine，is a central nervous system stimulant, mainly used in preworkout supplement and weight loss ingredients. According to the FDA, there have been too many public complaints about products containing DMAA, and even people died. DMAA is said to be synthetic and harmful to human body as a dietary supplement. That’s why dendrobium extracts are now in the supplement formula. The sports nutrition manufacturers just want to replace the DMAA. Therfore, is dendrobium powerful?

Health Benefits of Dendrobium extract

Dendrobiu Extract works in a few ways

1.Elevate your mood. One thing that most bodybuilders will notice is that it puts you in a good mood. This is because it has naturally occurring forms of Phenylethylamine. Phenylethylamine is known to help boost mood and increase focus, but when taken in high dosages it makes you feel happy. It like that old you that you haven’t seen in a while the you that still fits in the old pair of jeans that make your butt look good. Phenylethylamine reacts differently with each user and makes some people feel more alert and focused, where other users have noticed that it makes them feel confident.

2.Boost your metabolism. Dendrobium extract is a stimulant, but unlike other stimulants it doesn’t restrict blood flow. If you need a boost before you go to the gym, using Dendrobium Extract instead of caffeine or in cohesion with caffeine you can actually achieve better results. When you restrict veins, it is a disadvantage to the muscles. The muscles need the nutrients from the veins, but if the veins are tight then it makes it more difficult to recover and get to the next set, or more weight. Using Dendrobium Extract instead helps give you energy and doesn’t restrict you from achieving better results in the gym.

3. Enhanced Energy Level

4. other benefits. In traditional Chinese Herb medicine, dedrobium is used to cure various diseases. It functions with Healing properties, Skin enhancing effect, Improved breathing capability, Improved bodily functions and Increased functioning of body.

Stanford Ingredients Co., Ltd is one of the manufacturers of DMAA in China, and we are now focusing on the latest raw ingredients for sports nutrition industry. Dendrobium extract with specifications 1%, 5%,20% are available in our stock.