hordenine hcl
Chemical Name:
N,N-dimethyl-4-hydroxy-phenethylamine or N,N-dimethyltyramine
CAS number: 6027-23-2
Specification:99%
Synonyms: N,N-dimethyltyramine hcl, hordenine
hydrochloride
Molecular Formular: C10H16ClNO
Molecular Weight: 201.69
What is hordenine hcl?
Hordenine, as described in Wikipedia, is a
natural alkaloid of the phenethylamine found in many plants, and mostly
commonly in barley. Chemically, hordenine is the N-methyl derivative of
N-methyltyramine, and the N,N-dimethyl derivative of the well-known biogenic
amine tyramine, from which it is biosynthetically derived and with which it
shares some pharmacological properties. while hordenine is best known as a
central nervous stimulant that assists in weight loss in sports nutriton
supplements.
What is the differences between hordenine and
hordenine HCL?
There is little difference in application
and stability between these two products. The HCL form is more water soluble
and more easily absorbed by the body due to its acidic character; thus making
it more expensive. In addition, the CAS number of hordenine hcl is 6027-23-2
while CAS number for hordenine is 3595-05-9. Chemically speaking, they are two
different products although their propertities are similar. If for hordenine
alone, we call it hordenine base.
How does hordenine hcl work?
Hordenine HCl is its ability to inhibit the
activity of Monoamine Oxidase B (MAO-B). MAO-B is an enzyme located in the
mitochondrial outer membrane. It catalyzes the oxidative deamination of
biogenic and xenobiotic amines and plays an important role in the metabolism of
neuroactive and vasoactive amines in the central nervous system and peripheral
tissues. This enzyme preferentially degrades benzylamine and phenylethylamine.
Like MAO-A, MAO-B also degrades dopamine. Usually this degradation function of
MAO-B is negative for pre-workout ingredients.
With this MAO-B inhibiting ability,
Hordenine HCl may prevent stimulant tolerance by decreasing the effect of
monoamine oxidase, thus Hordenine HCl can prevent the breakdown of many
stimulants and make them more effective.
Benefits of taking hordenine hcl
Hordenine HCL is used as a stimulant, a
stimulant tolerance inhibitor, and for weight loss. Hordenine HCL may assist
with weight loss, in part, by encouraging the release of norepinephrine.
Norepinephrine is an excitatory hormone and is lipolytic, which means it helps
release fat from fat cells that are oxidized, therefore increasing energy and
reducing overall fat on the body. The
key benefits of hordenine hcl are sumarrized as below:
1.Enhance
energy as a stimulant.
Hordenine hcl, especially when taken with
caffeine, has a stimulant effect, helping to provide energy. This could keep
you awake longer and aid in concentration in areas where becoming tired too
early might be a problem.
2.Lose
weight
The increased metabolism efficiency has
been known to actually lower some people’s appetites, making weight loss
considerably easier. When someone is just less hungry, weight loss is something
that just happens as a matter of course.
3.
Appetite Control
It can be a difficult feat to keep urges
and cravings for various foods under control during a diet or training. The
problem is for certain regimens to be successful, sticking as closely as
possible to a particular diet can be critical. Having a supplement like
Hordenine to help take the edge off of appetite surges can make it much easier
to stick to your regimen.
Dosage of Hordenine HCL
Start with 25mg daiy and adjust dosage up
or down depending on results. It is common to mix Hordenine with caffeine such as
in coffee. This helps extend the effect.
Some possible side effects of hordenine
that have been reported are nausea, insomnia, dizziness, anxiety, upset
stomach, mood swings, and rapid heart rate.
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