Tuesday, March 26, 2013

Sulbutiamine- nootropic


Sulbutiamine
CAS No.: 3286-46-2
Synonyms: Arcalion, Enerion, Bisibuthiamine, Youvitan
Molecular Formula:C32H46N8O6S2
Molecular Weight: 702.89

What is Sulbutiamine?
Sulbutiamine, accordingto wikipedia, as a synthetic derivative of thiamine (vitamin B1), it is a lipophilic compound that crosses the blood–brain barrier more readily than thiamine and increases the levels of thiamine and thiamine phosphate esters in the brain.

Does Sulbutiamine work?
Sulbutiamine, similar to coffee, easily crosses a person's blood brain barrier. This enables these two drugs to contact your mind and produce an extremely apparent effect. Both of these supplements then impact quantities/effects of distinct neurotransmitters in your brain. Neurotransmitters are the brain's manner of interacting with itself. Theoretically, in the event that an individual had zero neurotransmitters, you would be wholly brain dead.

Caffeine minimizes the effects involving the neurotransmitter adenosine. Because adenosine helps bring about sleep and inhibits alertness, caffeine will give you a rush of energy. Nonetheless, it won't affect the numbers of adenosine, it merely keeps their effects in check. While the caffeine wears away, the adenosine begins to be effective yet again, and you will most certainly crash.

Sulbutiamine effects absolutely different neurotransmitters. It raises amounts of ACh, GABA, and Glutamate. GABA improves mood plus reduces stress and anxiety. Glutamate and ACh work together to improve a person's memory and decrease levels of fatigue.

Benefits of taking Sulbutiamine supplement:
Sulbutiamine is a nootropic designed to give you more energy, improve your mood, and boost your memory.  The detailed benefits are summarized as below:

1.boost more energy
Sulbutiamine’s nootropic properties boost both physical and mental levels in the body leaving you with a feeling of high energy. It is used primarily to treat a condition called asthenia and fatigue.

2.improve mood
Sulbutiamine is another great nootropic to help with mood. Some people have compared Sulbutiamine to MDMA’s anxiolytic and anti-depressant qualities without the amphetamine stimulation. This is a rather bold statement but is likely proof that this B1 Vitamin derived nootropic may have some great mood boosting qualities. Sulbutimaine defiantly works for some and has been prescribed in countries outside North America to help with depression.
Sulbutiamine’s effects on mood are likely related to effects it has on dopamine. This nootropic increases dopamine and dopamine (D1) receptor density in the prefrontal cortex. Dopamine transmission problems are often a cause of depression. This would explain Sulbutiamines’ effects on possible mood improvement. It was also seen in a study to reduce behavioural inhibitions which are commonly seen in peoples with shyness and depression.

3.boost memory
Also from wikipeidia reference citation, Several studies have shown that sulbutiamine improves memory through the potentiation of cholinergic, dopaminergic, and glutamatergic transmission. When sulbutiamine is administered to mice, they perform better on operant conditioning tests[14] and object recognition tests.[15] Sulbutiamine also reduces the amnesiac effects of dizocilpine and improves memory in schizophrenics.

4. Erectile dysfunction
According to one recent study, sulbutiamine is effective for the treatment of psychogenic erectile dysfunction.

Sulbutiamine Dosage
The recommended Sulbutiamine dosage is usually 600 mg per day, taken in three 200 mg doses, one in the morning and one in the afternoon and another in the evening. It is sold in tablet capsule and powder form, generally in doses 200 mg each.

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